Publications

Click on plus icons to expand.

Manuscripts

Costanzo MR, Ponikowski P, Javaheri S, et al. Randomised Controlled Trial of Transvenous Neurostimulation for Central Sleep Apnoea. The Lancet 2016;388:974–82.

Jagielski D, Ponikowski P, Augostini R, et al. Long-Term Safety and Efficacy of Transvenous Stimulation of the Phrenic Nerve for the Treatment of Central Sleep Apnea: Experience with the remedē® System. Eur J Heart Fail 2016 DOI: 10.1002/ejhf.593.

Joseph S, Costanzo MR. A novel therapeutic approach for central sleep apnea: Phrenic nerve stimulation by the remedē® System. International Journal of Cardiology 2016;206:S28–S34.

Costanzo MR, Augostini R, Goldberg LR, et al. Design of the remedē® System Pivotal Trial: A Prospective, Randomized Study in the Use of Respiratory Rhythm Management to Treat Central Sleep Apnea. J Card Fail 2015;21:892-902.

Zhang XL, Ding N, Ni B, et al. Safety and feasibility of chronic transvenous phrenic nerve stimulation for treatment of central sleep apnea in heart failure patients. Clin Respir J 2015; DOI:10.1111/crj. 12320.

Abraham WT, Jagielski D, Oldenburg O, et al. Phrenic Nerve Stimulation for the Treatment of Central Sleep Apnea. JCHF 2015;5:360-369.

Germany R, Joseph S, James K, Kao A. A Novel Therapeutic Approach for the Treatment of Central Sleep Apnea: the remedē® System. Cardiovascular Revascularization Med 2014;15:235-239.

Khayat R, Small R, Rathman L, et al. Sleep-Disordered Breathing in Heart Failure: Identifying and Treating an Important but Often Unrecognized Comorbidity in Heart Failure Patients. Journal of Cardiac Failure 2013;19:431-444.

Ponikowski P, Javaheri S, Michalkiewicz D, et al. Transvenous phrenic nerve stimulation for the treatment of central sleep apnoea in heart failure. Eur Heart J 2012;33:889-894.

Emani S and Abraham WT. Tranvenous phrenic nerve stimulation – a novel therapy for central sleep apnea in heart failure. European Cardiology 2012;8:44-50.

Zhang XL, Ding N, Wang H, et al. Transvenous phrenic nerve stimulation in patients with Cheyne-Stokes respiration and congestive heart failure – a safety and proof-of-concept study. Chest 2012; 142:927-934.

Bramate CT, Westlund R, Weinhaus A. Suitability of the pericardiophrenic veins for phrenic nerve stimulation: an anatomic study. Neuromodulation 2011;14:337-342.

Abstracts

Pleister A, Hasan A, Khayat R, James K, Abraham WT.  Changes in Thoracic Impedance Measured via the Azygos Vein with the remedē® System Indicate Worsening Heart Failure.  Journal of  Cardiac Failure 2014;20:S111-112.

Ponikowski P, Krueger S, Oldenburg O, Germany R, Abraham WT.  Prevalence of Central Sleep Apnea in Patients Screened During the remedē® System Pilot Study.  J Cardiac Failure 2014;20:S117-118.

Abraham WT, Oldenburg O, Jagielski D, Augostin R, Krueger S, Kolodziej A, Gutleben KJ, Khayat R, Merliss A, Ponikowski P, on Behalf of the remedē® System Pilot Study Investigators. The Long Term Effects of the remede System in the Treatment of Central Sleep Apnea. European Journal of Heart Failure 2014.

Oldenburg O, Abraham WT, Krueger S, Bourn D, Ponikowski P on Behalf of the remedē® System Pilot Study Investigators. Significant Chronic Improvements in Sleep Quality Shown in Central Sleep Apnea in Patients when Treated with a Respiratory Rhythm Management System. European Journal of Heart Failure 2014; P230.

Augostini R, Merliss A, Jagielski D, Bourn D, Abraham WT, and Ponikowski P. Comparison of Right versus Left Phrenic Nerve Stimulation in Patients Implanted with the remedē® System. Heart Rhythm Society 2014.

Abraham WT, Jagielsk D, Oldenburg O, Augostini R, Krueger S, Kolodziej A, Gutleben KJ, Khayat R, Merliss A, Javaheri S, Germany R, Ponikowski P. The Effects of Chronic Implanted Transvenous Phrenic Nerve Stimulation in Central Sleep Apnea: the remedē® System Pilot Study. Journal of Cardiac Failure 2013.

Gutleben KJ, Bitter T, Krause B, Prib N, Horstkotte D, Oldenburg O. Transvenous phrenic nerve stimulation to treat central sleep apnea in chronic heart failure: feasibility of accessing the left pericardiophrenic vein for lead placement from either the right or left subclavian vein. German Pacing Society 2011.

Johnson N, Petersen-Stejskal S, Germany R. Prevalence of central sleep apnea ins heart failure patients in the era of beta-blockers. Heart and Lung 2010; 39 (4):375.

Jagielski D, Augostini R, Berger R, Henrikson C, Crossley G, Schloss E, Love C, Michalkiewicz D, Jastrebski M, Yip G, Westlund R, Johnson N. Identification of the left pericardiophrenic vein and related vascular structures. J Cardiac Fail 2010; 16(8 Supp): S59.

Oldenburg O, Michalkiewicz D, Bart B, Hasan A, Czarnecka D, Abraham WT, Ponikowski P. Transvenous phrenic nerve stimulation to treat central sleep apnea: initial experience. German Society of Sleep Medicine.

Westlund R, Bramante C, Weinhaus A. Anatomical variations of the left pericardiophrenic vein and related vascular structures. J Cardiac Fail 2010; 16 (8 Supp): S28.

James K, Panteleon A, Augostini R, Jagielski D, Michalkiewicz D. Transvenous Ventilation Monitoring Using Transthoracic Impedance and a Novel Lead Placement. Heart Rhythm 2010 7 (5 Supp): S243.

1 in 3 people with heart failure have Central Sleep Apnea and stop breathing during the night. Talk to your doctor about the remedē® System clinical study to see if you qualify.
Send us an email at info@respicardia.com or read about our clinical study at www.clinicaltrials.gov.

CONTACT US

Respicardia®, Inc.
12400 Whitewater Dr., Suite 150
Minnetonka, MN 55343 USA
See Map
Phone: +1-952-540-4470
E-mail: info@respicardia.com
©2017 Respicardia®, Inc. CAUTION: Investigational Device. Limited by Federal (or United States) Law to investigational use.